Doctor
November 2023 – New Scientific Discovery
Scientists From Yale School Of Medicine Have Made A Remarkable Discovery Which Has Identified The Key Reason For Belly Fat, And Its Not What You Think…
Researches from Yale School of Medicine discovered that An enzyme found in the brain acts as a major regulator of body weight, In a new study, they found that removing the enzyme from neurons in a part of the brain known as the hypothalamus led to gain weight and burn less fat. This finding, they say, suggests that the enzyme OGT could be a target for treating metabolic disease.

“This suggested that OGT plays an important role as a nutrient sensor in this neuron population,” said Xiaoyong Yang, professor of comparative medicine and of cellular and molecular physiology at Yale School of Medicine and senior author of the study.

When the body has adequate amounts of food, its preferred fuel is glucose. “But when you fast, your glucose runs out quickly,” explained Yang. The body then taps into its fat stores in order to meet energy demands.

“Without OGT, the body can’t sense that less food is coming in, and then it doesn’t tell its fat tissues to burn fat,” said Yang.

Yang likens OGT to a thermostat, or a “metastat,” as he calls it, since OGT is crucial for metabolic homeostasis.

You set a thermostat to the temperature you’d like a room to be. In the summer, as your room begins to heat up, your air conditioner kicks in to return the room to the temperature you’ve programmed.

OGT is like a metastat, Yang says, working to keep the body’s weight at its set point. “And that set point will be different from individual to individual,” he said. While a person’s weight can fluctuate from time to time, the body’s metabolic processes work to keep the weight around its set point.

“So if you eat a big meal, for example, your body recognizes that and burns more calories to keep your weight at that set point,” said Yang. “And OGT is critical for setting that weight point.”

References:

1. https://pubmed.ncbi.nlm.nih.gov/4950199
2. https://pubmed.ncbi.nlm.nih.gov/824153
3. https://pubmed.ncbi.nlm.nih.gov/28585194

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Muira Puama
Green Tea
Healthiest beverage on the planet that has many amazing health benefits. It promotes weightloss.

Antioxidant compounds
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Increase in fat burn
Ginkgo Biloba
Berberine
Research suggests that it helps promote weight loss & enhance blood sugar regulation

Blood sugar regulation
Used for weightloss management
Contains strong antioxidants
Hawthorn
Resveratrol
Resveratrol has antioxidant and anti-inflammatory properties to protect you from diseases.

Free radical cellular damage
Strong antioxidant
Controls body inflammation
Damiana
Silybum
Silymarin is an antioxidant compound taken from milk thistle seeds. Its used to detox the liver.

Lowers cholesterol levels
Liver protection
Elevation of liver enzymes
Tribulus
Banaba
Banaba might reduce blood sugar and help the body use insulin more efficiently.

Anti-diabetic properties
Anti-obesity effects
Cholesterol-lowering
Catuaba
Capsicum
Capsicum is a good source of Vitamin B6 and magnesium.

Relieve anxiety
Manage panic attacks
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Security Payments.

$199 $69
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+ SHIPPING

6 BOTTLES
180 Day Supply
1 bottle
$39
/bottle

Security Payments.

$1194 $234
Shipping
+ FREE SHIPPING

3 BOTTLES
90 Day Supply
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Security Payments.

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Shipping
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Scientific References

1. Saper, C.B. and Lowell, B.B., 2014. The hypothalamus. Current Biology, 24(23), pp.R1111-R1116.
2. Puelles, L., Martinez-De-La-Torre, M., Bardet, S. and Rubenstein, J.L.R., 2012. Hypothalamus. In The mouse nervous system (pp. 221-312). Academic Press.
3. Velloso, L.A., Araújo, E.P. and de Souza, C.T., 2008. Diet-induced inflammation of the hypothalamus in obesity. Neuroimmunomodulation, 15(3), pp.189-193.
4. De Souza, C.T., Araujo, E.P., Bordin, S., Ashimine, R., Zollner, R.L., Boschero, A.C., Saad, M.J. and Velloso, L.A., 2005. Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus. Endocrinology, 146(10), pp.4192-4199.
5. Auvinen, H.E., Romijn, J.A., Biermasz, N.R., Havekes, L.M., Smit, J.W.A., Rensen, P.C.N. and Pereira, A.M., 2011. Effects of high fat diet on the Basal activity of the hypothalamus-pituitary-adrenal axis in mice: a systematic review. Hormone and metabolic research, pp.899-906.
6. Velloso, L.A. and Schwartz, M.W., 2011. Altered hypothalamic function in diet-induced obesity. International journal of obesity, 35(12), pp.1455-1465.
7. Braillon, A., Capron, J.P., Herve, M.A., Degott, C. and Quenum, C., 1985. Liver in obesity. Gut, 26(2), pp.133-139.
8. Scheen, A.J. and Luyckx, F.H., 2002. Obesity and liver disease. Best practice & research Clinical endocrinology & metabolism, 16(4), pp.703-716.
9. Chiang, D.J., Pritchard, M.T. and Nagy, L.E., 2011. Obesity, diabetes mellitus, and liver fibrosis. American Journal of Physiology-Gastrointestinal and Liver Physiology, 300(5), pp.G697-G702.
10. Jakobsen, M.U., Berentzen, T., Sørensen, T.I.A. and Overvad, K., 2007. Abdominal obesity and fatty liver. Epidemiologic reviews, 29(1), pp.77-87.
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